top of page

Publications

a.jpg

Magnetic stirring with iron oxide nanospinners accretes neurotoxic Aβ42 oligomers into phagocytic clearable plaques for Alzheimer's disease treatment

Arjun Sabu, Yu Ching Huang, Ramalingam Sharmila, Chih-Yuan Sun, Min-Ying Shen*, Hsin-Cheng Chiu*, 2024, Materials Today Bio, 28, 101213

IF = 8.7

DOI: https://doi.org/10.1016/j.mtbio.2024.101213

image.png

Nanomedicines Targeting Glioma Stem Cells

Arjun Sabu, Te-I Liu, Siew Suan Ng, Ruey-An Doong, Yu-Fen Huang*, and Hsin-Cheng Chiu*, 2023, ACS Applied Materials & Interfaces, 15(1), 158-181

IF = 10.383

DOI: https://doi.org/10.1021/acsami.2c03538

image.png

Photothermal/NO combination therapy from plasmonic hybrid nanotherapeutics against breast cancer

Reesha Kv, Chun-Liang Lo , Hsin-Hung Chen, Ming-Yin Shen, Ying-Chieh Yang, Arjun Sabu,  Yu-Feng Huang, Hsin-Cheng Chiu*2022, Journal of Controlled Release, 345, 417 432

IF = 11.467

DOI: https://doi.org/10.1016/j.jconrel.2022.03.030

b.jpg

Microfluidized Dextran Microgels Loaded with Cisplatin/SPION Lipid Nanotherapeutics for Local Colon Cancer Treatment via Oral Administration

I.-Lin Lu, Ting-Wei Yu, Te-I Liu, Hsin-Hung Chen, Ying-Chieh Yang, Chun-Liang Lo, Chi-Ya Wang, and Hsin-Cheng Chiu*,2022, Advanced Healthcare Materials, 11, 2201140.

IF = 10.0

DOI: https://doi.org/10.1002/adhm.202201140

1-s2.0-S016836592030479X-ga1_lrg.jpg

Tumor microenvironment-responsive and oxygen self-sufficient oil droplet nanoparticles for enhanced photothermal/photodynamic combination therapy against hypoxic tumors.

Reesha Kv, Te-I Liu, I.-Lin Lu, Chia-Chen Liu, Hsin-Hung Chen, Ting-Yu Lu, Wen-Hsuan Chiang, Hsin-Cheng Chiu*2020, Journal of Controlled Release, 328, 87-99.

IF = 11.467

DOI: https://doi.org/10.1016/j.jconrel.2020.08.038

73

New combination treatment from ROS-induced sensitized radiotherapy with nanophototherapeutics to fully eradicate orthotopic breast cancer and inhibit metastasis.

Te-I Liu, Ting-Yu Lu, Ying-Chieh Yang, Siou-Han Chang, Hsin-Hung Chen, I. Lin Lu, Arjun Sabu, and Hsin-Cheng Chiu*2020, Biomaterials, 257, 120229.

IF = 12.479

DOI: https://doi.org/10.1016/j.biomaterials.2020.120229

71.gif

Combo-targeted nanoassemblies as a chemotherapy delivery system against peritoneal carcinomatosis colorectal cancer.

Ming-Yin Shen, Siou-Han Chang, Te-I Liu, Ting-Yu Lu, Arjun Sabu, Hsin-Hung Chen and Hsin-Cheng Chiu*2020, Biomaterials Science, 8, 3885-3895

IF = 7.59

DOI: https://doi.org/10.1039/D0BM00583E

Alendronate/folic acid-decorated polymeric nanoparticles for hierarchically targetable chemotherapy against bone metastatic breast cancer.

Shih-Hong Chen, Te-I Liu, Cheng-Ling Chuang, Hsin-Hung Chen, Wen-Hsuan Chiang, Hsin-Cheng Chiu*2020, Journal of Materials Chemistry B, 8, 3789-3800

IF = 7.571

DOI: https://doi.org/10.1039/D0TB00046A

Dual stimuli-guided lipid-based delivery system of cancer combination therapy.

 

Te-I Liu, Ting-Yu Lu, Siou-Han Chang, Ming-Yin Shen, Hsin-Cheng Chiu*2020, Journal of Controlled Release, 318, 16-24.

IF = 11.467

DOI: https://doi.org/10.1016/j.jconrel.2019.12.002

  1. Arjun Sabu, Manoj Kandel, Ritwick Ranjan Sarma, Lakshminarayan Ramesan, Ekta Roy, Ramalingam Sharmila, Hsin-Cheng Chiu*, Heterojunction semiconductor nanocatalysts as cancer theranostics, APL bioengineering, 2024, 8(4).

  2. Siew Suan Ng, Ian Sandall, Hsin-Cheng Chiu*, Ruey-an Doong*, Peroxidase-like molybdenum oxides/nitrogen-doped graphene quantum dot as the smartphone-based immunosensing probe for the ultrasensitive detection of neurofilament light chain in human serum, Sensors and Actuators B: Chemical, 2024, 419, 136426.

  3. Arjun Sabu, Yu Ching Huang, Ramalingam Sharmila, Chih-Yuan Sun, Min-Ying Shen*, Hsin-Cheng Chiu*, Magnetic stirring with iron oxide nanospinners accretes neurotoxic Aβ42 oligomers into phagocytic clearable plaques for Alzheimer's disease treatment, Materials Today Bio, 2024, 28, 101213.

  4. Hsin-Hung Chen, Chen-Hsiang Sang, Chang-Wei Chou, Yi-Ting Lin, Yi-Shou Chang, Hsin-Cheng Chiu*, Solid lipid nanoparticles loaded with dexamethasone palmitate for pulmonary inflammation treatment by nebulization approach, Pharmaceutics, 2024, 16(7), 878.

  5. Yu-Wei Yen, Yi-Lin Lee, Lu-Yi Yu, Cheng-En Li, Pei-Wei Shueng, Hsin-Cheng Chiu, Chun-Liang Lo, Fucoidan/chitosan layered PLGA nanoparticles with melatonin loading for inducing intestinal absorption and addressing triple-negative breast cancer progression, International Journal of Biological Macromolecules, 2023, 250, 126211.

  6. Lu-Yi Yu, Pei-Wei Shueng, Hsin-Cheng Chiu, Yu-Wei Yen, Tzu-Yu Kuo, Chieh-Ru Li, Ming-Wei Liu, Chia-Hsin Ho, Tzu-Hao Ho, Bo-Wei Wang, Cheng-En Li, Ming-Hung Chen, Yao-An Shen, Chun-Liang Lo, Glucose transporter 1-mediated transcytosis of glucosamine-labeled liposomal ceramide targets hypoxia niches and cancer stem cells to enhance therapeutic efficacy, ACS Nano, 2023, 17, 14, 13158–13175. 

  7. Arjun Sabu, Te-I Liu, Siew Suan Ng, Ruey-An Doong, Yu-Fen Huang,* and Hsin-Cheng Chiu*, Nanomedicines Targeting Glioma Stem Cells, ACS Appl. Mater. Interfaces, 2023, 15, 1, 158–181. 

  8. I.-Lin Lu, Ting-Wei Yu, Te-I Liu, Hsin-Hung Chen, Ying-Chieh Yang, Chun-Liang Lo, Chi-Ya Wang, and Hsin-Cheng Chiu*, Microfluidized Dextran Microgels Loaded with Cisplatin/SPION Lipid Nanotherapeutics for Local Colon Cancer Treatment via Oral Administration, Advanced Healthcare Materials, 2022, 11, 2201140.

  9. Yu-Han Wen, Po-I Hsieh, Hsin-Cheng Chiu, Chil-Wei Chiang, Chun-Liang Lo, Yi-Ting Chiang, Precise delivery of doxorubicin and imiquimod through pH-responsive tumor microenvironment-active targeting micelles for chemo and immunotherapy, Materials Today Bio, 2022, 17, 100482. 

  10. Bo-Wei Chen, Shadie Hatamie, Hsin-Cheng Chiu, Zung-Hang Wei, Shang-Hsiu Hu* and Da-Jeng Yao*, Shape-mediated magnetocrystalline anisotropy and relaxation controls by cobalt ferrite core–shell heterostructures for magnetothermal penetration delivery, Advanced Materials Interfaces, 2022, 2200022. 

  11. Pei-Wei Shueng, Lu-Yi Yu, Hsiao-Hsin Hou, Hsin-Cheng Chiu and Chun-Liang Lo, Charge conversion polymer–liposome complexes to overcome the limitations of cationic liposomes in mitochondrial-targeting drug delivery, International Journal of Molecular Sciences, 2022, 23, 3080-3098. 

  12. Reesha Kakkadavath Vayalakkara, Chun-Liang Lo, Hsin-Hung Chen, Ming-Yin Shen, Ying-Chieh Yang, Arjun Sabu, Yu-Feng Huang*, Hsin-Cheng Chiu*, Photothermal/NO combination therapy from plasmonic hybrid nanotherapeutics against breast cancer, Journal of Controlled Release, 2022, 345, 417–43. 

  13. Keiko Tezuka, Masakazu Umezawa*, Te-I Liu, Koki Nomura, Kyohei Okubo, Hsin-Cheng Chiu, Masao Kamimura, and Kohei Soga*, Upconversion luminescent nanostructure with ultrasmall ceramic nanoparticles coupled with rose bengal for NIR-induced photodynamic therapy, ACS Applied Bio Materials, 2021, 4, 4462-4469. 

  14. Arjun Sabu, Jui-Yen Lin, Ruey-An Doong, Yu-Fen Huang* and Hsin-Cheng Chiu*, Prospects of an engineered tumor-targeted nanotheranostic platform based on NIR-responsive upconversion nanoparticles, Materials Advances, 2021, 2, 7101–7117. 

  15. Pei-Wei Shueng, Lu-Yi Yu, Hsin-Cheng Chiu, Hui-Ching Chang, Yen-Ling Chiu, Tzu-Yu Kuo, Yu-Wei Yen, Chun-Liang Lo*, Early phago-/endosomal escape of platinum drugs via ROS-responsive micelles for dual cancer chemo/immunotherapy, Biomaterials, 2021, 276, 121012. 

  16. Shiou-Fen Hung, Yu-Han Wen, Lu-Yi Yu, Hsin-Cheng Chiu, Yi-Ting Chiang* and Chun-Liang Lo*, Development of a rapid-onset, acid-labile linkage polyplex-mixed micellar system for anticancer therapy, Polymers, 2021, 13, 1823. 

  17. Te-I Liu, Ting-Yu Lu, Ying-Chieh Yang, Siou-Han Chang, Hsin-Hung Chen, I.-Lin Lu, Arjun Sabu, Hsin-Cheng Chiu*, New combination treatment from ROS-induced sensitized radiotherapy with nanophototherapeutics to fully eradicate orthotopic breast cancer and inhibit metastasis. Biomaterials, 2020, 257, 120229. 

  18. Reesha Kv, Te-I Liu, I.-Lin Lu, Chia-Chen Liu, Hsin-Hung Chen, Ting-Yu Lu, Wen-Hsuan Chiang, Hsin-Cheng Chiu*, Tumor microenvironment-responsive and oxygen self-sufficient oil droplet nanoparticles for enhanced photothermal/photodynamic combination therapy against hypoxic tumors. Journal of Controlled Release, 2020, 328, 87-99. 

  19. Ming-Yin Shen, Siou-Han Chang, Te-I Liu, Ting-Yu Lu, Arjun Sabu, Hsin-Hung Chen, Hsin-Cheng Chiu*, Combo-targeted nanoassemblies as a chemotherapy delivery system against peritoneal carcinomatosis colorectal cancer, Biomaterials Science, 2020, 8, 3885-3895. 

  20. Te-I Liu, Ting-Yu Lu, Siou-Han Chang, Ming-Yin Shen, Hsin-Cheng Chiu*, Dual stimuli-guided lipid-based delivery system of cancer combination therapy, Journal of Controlled Release, 2020, 318, 16-24. (SCI)

  21. Shih-Hong Chen, Te-I Liu, Cheng-Ling Chuang, Hsin-Hung Chen, Wen-Hsuan Chiang, Hsin-Cheng Chiu*, Alendronate/folic acid-decorated polymeric nanoparticles for hierarchically targetable chemotherapy against bone metastatic breast cancer, Journal of Materials Chemistry B, 2020, 8, 3789-3800. (SCI)

  22. Te-I Liu, Yuan-Chung Tsai, Te-Ming Wang, Siou-Han Chang, Ying-Chieh Yang, Hsin-Hung Chen, Hsin-Cheng Chiu*, Development of a nano-immunomodulator encapsulating R837 and caffeine for combined radio-/immunotherapy against orthotopic breast cancer. Progress in Natural Science: Materials International, 2020, 30, 697-706. 

  23. Yuan-Chung Tsai, Jing-Chian Luo, Te-I Liu, I.-Lin Lu, Ming-Yin Shen, Chun-Yu Chuang, Chorng-Shyan Chern, Hsin-Cheng Chiu*, Capturing amyloid-β oligomers by stirring with microscaled iron oxide stir bars into magnetic plaques to reduce cytotoxicity toward neuronal cells. Nanomaterials, 2020, 10, 1284. 

  24. I-Lin Lu, Te-I Liu, Hsiao-Chieh Lin, Siou-Han Chang, Chun-Liang Lo, Wen-Hsuan Chiang, Hsin-Cheng Chiu*, IR780-loaded zwitterionic polymeric nanoparticles with acidity-induced agglomeration for enhanced tumor retention, European Polymer Journal, 2020, 122, 109400. (SCI)

  25. Ming-Yin Shen, Te-I Liu, Ting-Wei Yu, Reesha Kv, Wen-Hsuan Chiang, Yuan-Chung Tsai, Hsin-Hung Chen, Sung-Chyr Lin, Hsin-Cheng Chiu*, Hierarchically targetable polysaccharide-coated solid lipid nanoparticles as an oral chemo/thermotherapy delivery system for local treatment of colon cancer, Biomaterials, 2019, 197, 86-100. (SCI)

  26. Hsin-Hung Chen, I.-Lin Lu, Te-I Liu, Yuan-Chung Tsai, Wen-Hsuan Chiang, Sung-Chyr Lin, Hsin-Cheng Chiu*, Indocyanine green/doxorubicin-encapsulated functionalized nanoparticles for effective combination therapy against human MDR breast cancer, Colloids and Surfaces B: Biointerfaces, 2019, 177, 294-305. (SCI)

  27. Kai-Ting Hou, Te-I Liu, Hsin-Cheng Chiu, Wen-Hsuan Chiang*, DOX/ICG-carrying γ-PGA-g-PLGA-based polymeric nanoassemblies for acid-triggered rapid DOX release combined with NIR-activated photothermal effect, European Polymer Journal, 2019, 110, 283-292. (SCI)

  28. Te-I Liu, Ying-Chieh Yang, Wen-Hsuan Chiang, Chun-Kai Hung, Yuan-Chung Tsai, Chi-Shiun Chiang, Chun-Liang Lo, Hsin-Cheng Chiu*, Radiotherapy-controllable chemotherapy from reactive oxygen species-responsive polymeric nanoparticles for effective local dual modality treatment of malignant tumors, Biomacromolecules, 2018, 19, 3825-3839.

  29. Ankan Dutta Chowdhury, Akhilesh Babu Ganganboina, Yuan-Chung Tsai, Hsin-Cheng Chiu*, Ruey-An Doong*, Multifunctional GQDs- concanavalin A@Fe3O4 nanocomposites for cancer cells detection and targeted drug delivery, Analytica Chimica Acta, 2018, 1027, 109-120.

  30. Te-I Liu, Ying-Chieh Yang, Wen-Hsuan Chiang, Chun-Kai Hung, Yuan-Chung Tsai, Chi-Shiun Chiang, Chun-Liang Lo, Hsin-Cheng Chiu*, Radiotherapy-controllable chemotherapy from reactive oxygen species-responsive polymeric nanoparticles for effective local dual modality treatment of malignant tumors, Biomacromolecules, 2018, 19, 3825-3839. 

  31. Yuan-Chung Tsai, Priya Vijayaraghavan, Wen-Hsuan Chiang, Hsin-Hung Chen, Te-I Liu, Ming-Yin Shen, Ayumu Omoto, Masao Kamimura, Kohei Soga*, and Hsin-Cheng Chiu*, Targeted delivery of functionalized upconversion nanoparticles for externally triggered photothermal/photodynamic therapies of brain glioblastoma, Theranostics, 2018, 8, 1435-1448. 

  32. Masao Kamimura,* Ayumu Omoto, Hsin-Cheng Chiu, and Kohei Soga*, Enhanced red upconversion emission of NaYF4:Yb3+, Er3+, Mn2+ nanoparticles for near-infrared induced photodynamic therapy and fluorescence imaging, Chemistry Letters, 2017, 46, 1076-1078.

  33. Yu-Lin Su, Ting-Wei Yu, Wen-Hsuan Chiang, Hsin-Cheng Chiu, Chun-Hsiang Chang, Chi-Shiun Chiang, Shang-Hsiu Hu, Hierarchically targeted and penetrated delivery of drugs to tumors by size-changeable graphene quantum dot nanoaircrafts for photolytic therapy, Advanced Functional Materials, 2017, 27, 1700056. (SCI)

  34. Wen-Chia Huang, I-Lin Lu, Wen-Hsuan Chiang, Yi-Wen Lin, Yuan-Chung Tsai, Hsin-Hung Chen, Chien-Wen Chang, Chi-Shiun Chiang, Hsin-Cheng Chiu*, Tumortropic adipose-derived stem cells carrying smart nanotherapeutics for targeted delivery and dual-modality therapy of orthotopic glioblastoma, Journal of Controlled Release, 2017, 254, 119-130. (SCI)

  35. Wen-Chia Huang, Shih-Hong Chen, Wen-Hsuan Chiang, Chu-Wei Huang, Chun-Liang Lo, Chorng-Shyan Chern, Hsin-Cheng Chiu*, Tumor microenvironment-responsive nanoparticle delivery of chemotherapy for enhanced selective cellular uptake and transportation within tumor, Biomacromolecules, 2016, 12, 3883-3892. (SCI)

  36. Ting-Wei Yu, I.-Lin Lu, Wen-Chia Huang, Shang-Hsiu Hu, Chia-Chian Hung, Wen-Hsuan Chiang and Hsin-Cheng Chiu*, Acidity-triggered surface charge neutralization and aggregation of functionalized nanoparticles for promoted tumor uptake, RSC Advances, 2016, 6, 36293-36295. (SCI)

  37. Chia-Chian Hung, Wen-Chia Huang, Yi-Wen Lin, Ting-Wei Yu, Hsin-Hung Chen, Sung-Chyr Lin, Wen-Hsuan Chiang*, and Hsin-Cheng Chiu*, Active tumor permeation and uptake of surface charge-switchable theranostic nanoparticles for imaging-guided photothermal/chemo combinatorial therapy, Theranostics, 2016, 6, 302–317. (SCI)

  38. Wen-Chia Huang, Ming-Yin Shen, Hsin-Hung Chen, Sung-Chyr Lin, Wen-Hsuan Chiang, Pei-Hsuan Wu, Chien-Wen Chang, Chi-Shiun Chiang and Hsin-Cheng Chiu*, Monocytic delivery of therapeutic oxygen bubbles for dual-modality treatment of tumor hypoxia, Journal of Controlled Release, 2015, 220, 738-750. (SCI)

  39. Wen-Chia Huang, Wen-Hsuan Chiang, Ya-Hui Cheng, Wan-Chi Lin, Ching-Fang Yu, Chia-Yi Yen, Chih-Kuang Yeh, Chorng-Shyan Chern, Chi-Shiun Chiang* and Hsin-Cheng Chiu*, Tumortropic monocyte-mediated delivery of echogenic polymer bubbles and therapeutic vesicles for chemotherapy of tumor hypoxia, Biomaterials, 2015, 71, 71-83. (SCI)

  40. Hsin-Hung Chen, Wen-Chia Huang, Wen-Hsuan Chiang, Te-I Liu, Ming-Yin Shen, Yuan-Hung Hsu, Sung-Chyr Lin* and Hsin-Cheng Chiu*, pH-Responsive therapeutic solid lipid nanoparticles for reducing p-glycoprotein-mediated drug efflux of MDR cancer cells, International Journal of Nanomedicine, 2015, 10, 5035-5048. (SCI)

  41. Wei-Hong Jian, Ting-Wei Yu, Chien-Ju Chen, Wen-Chia Huang, Hsin-Cheng Chiu*, and Wen-Hsuan Chiang*, Indocyanine green-encapsulated hybrid polymeric nanomicelles for photothermal cancer therapy, Langmuir, 2015, 31, 6202-10.(SCI)

  42. Wen-Chia Huang, Yung-Chu Chen, Yuan-Hung Hsu, Wen-Yuan Hsieh* and Hsin-Cheng Chiu*, Development of a diagnostic polymersome system for potential imaging delivery, Colloids and Surfaces B: Biointerfaces, 2015, 128, 67–76. (SCI)

  43. Yi-Fong Huang, Wen-Hsuan Chiang, Wen-Chia Huang, Hsin-Hong Chen, Ming-Yin Shen, Sung-Chyr Lin, Chorng-Shyan Chern, Hsin-Cheng Chiu*, pH-Responsive hierarchical transformation of charged lipid assemblies within polyelectrolyte gel layers with applications for controlled drug release and MR imaging contrast, Journal of Materials Chemistry B, 2014, 2, 4988-4992. (SCI)

  44. Wen-Hsuan Chiang, Wen-Chia Huang, Ming-Yin Shen, Che-Hsu Wang, Yi-Fong Huang, Sung-Chyr Lin, Chorng-Shyan Chern, Hsin-Cheng Chiu*, Dual-layered nanogel-coated hollow lipid/polypeptide conjugate assemblies for potential pH-triggered intracellular drug release, PLoS ONE, 2014, 9, e92268. (SCI)

  45. Wen-Hsuan Chiang, Viet Thang Ho, Hsin-Hung Chen, Wen-Chia Huang, Yi-Fong Huang, Sung-Chyr Lin, Chorng-Shyan Chern, and Hsin-Cheng Chiu*, Superparamagnetic hollow hybrid nanogels as a potential guidable vehicle system of stimuli-mediated MR imaging and multiple cancer therapeutics, Langmuir, 2013, 29, 6434−6443. (SCI)

  46. Wen-Hsuan Chiang, Wen-Chia Huang, Chien-Wen Chang, Ming-Yin Shen, Zong-Fu Shih, Yi-Fong Huang, Sung-Chyr Lin, and Hsin-Cheng Chiu*, Functionalized polymersomes with outlayered polyelectrolyte gels for potential tumor-targeted delivery of multimodal therapies and MR imaging, Journal of Controlled Release, 2013, 168 280–288. (SCI)

  47. Wen-Hsuan Chiang, Viet Thang Ho, Wen-Chia Huang, Yi-Fong Huang, Chorng-Shyan Chern, and Hsin-Cheng Chiu*, Dual stimuli-responsive polymeric hollow nanogels designed as carrier for intracellular triggered drug release, Langmuir, 2012, 28, 15056-15064. (SCI)

  48. Wen-Hsuan Chiang, Yu-Jen Lan, Yun-Chiao Huang, Yu-Wen Chen, Yi-Fong Huang, Sung-Chyr Lin, Chorng-Shyan Chern, and Hsin-Cheng Chiu*, Multi-scaled polymersomes from self-assembly of octadecanol-modified dextrans, Polymer, 2012, 53, 2233-2244. (SCI)

  49. Wen-Chia Huang, Wen-Husan Chiang, Su-Jen Lin, Yu-Jen Lan, Hsin-Lung Chen, Chrong-Shyan Chern, and Hsin-Cheng Chiu*, Lipid-containing polymer vesicles with pH/Ca2+ ions-manipulated size-selective permeability, Advanced Functional Materials, 2012, 22, 2267-2275. (SCI)

  50. Yi-Fong Huang, Wen-Husan Chiang, Pei-Ling Tsai, Chrong-Shyan Chern, and Hsin-Cheng Chiu*, Novel hybrid vesicles co-assembled from cationic lipid and PAAc-g-mPEG with pH-triggered transmembrane channels for controlled drug release, Chemical Communications, 2011, 47, 10978-10980. (SCI)

  51. Wen-Husan Chiang, Yuan-Hung Hsu, Chrong-Shyan Chern, and Hsin-Cheng Chiu*, Two-stage thermally induced stable colloidal assemblies from PAAc/PNIPAAm/mPEG graft copolymer in water, Polymer, 2011, 52, 2422-2429. (SCI)

  52. Wen-Chia Huang, Wen-Husan Chiang, Yi-Fong Huang, Sung-Chyr Lin, Zong-Fu Shih, Chrong-Shyan Chern, and Hsin-Cheng Chiu*, Nano-scaled pH-responsive polymeric vesicles for intracellular release of doxorubicin, Journal of Drug Targeting, 2011, 19, 944-53. (SCI)

  53. Yi-Fong Huang, Wen-Husan Chiang, Pei-Ling Tsai, Chrong-Shyan Chern, Hsin-Cheng Chiu*, Novel hybrid vesicles co-assembled from cationic lipid and PAAc-g-mPEG with pH-Triggered transmembrane channels for controlled drug release, Chemical Communications, 2011, 47, 10978-80.

  54. Wen-Husan Chiang, Yuan-Hung Hsu, Yi-Wei Chen, Chrong-Shyan Chern, Hsin-Cheng Chiu*, Thermoresponsive interpolymeric complex assemblies from co-association of linear PAAc-homopolymers with PNIPAAm segments containing PAAc-based graft copolymer, Macromolecular Chemistry and Physics, 2011, 212, 1869 (SCI)

  55. Wen-Husan Chiang, Yuan-Hung Hsu, Chrong-Shyan Chern, Hsin-Cheng Chiu*, Two-stage thermally induced stable colloidal assemblies from PAAc/PNIPAAm/mPEG graft copolymer in water, Polymer, 2011, 52, 2422 (SCI)

  56. Wen-Hsuan Chiang, Yuan-Hung Hsu, Fa-Fen Tang, Chorng-Shyan Chern, Hsin-Cheng Chiu*, Temperature/pH-induced morphological regulations of shell cross-linked graft copolymer assemblies, Polymer, 2010, 51, 6248-6257. (SCI)

  57. Wen-Husan Chiang, Yuan-Hung Hsu, Tzu-Wei Lou, Chorng-Shyan Chern, and Hsin-Cheng Chiu*, Effects of mPEG grafts on morphology and cross-linking of thermally induced micellar assemblies from PAAc-based graft copolymers in aqueous phase, Macromolecules, 2009, 42, 3611-3619. (SCI)

  58. Wen-Husan Chiang, Yuan-Hung Hsu, Chorng-Shyan Chern, and Hsin-Cheng Chiu*, Thermally induced polymeric assemblies from PAAc-based copolymer containing both PNIPAAm and mPEG grafts in water, J. Phys. Chem. B, 2009, 113, 4187-4196. (SCI)

  59. Ray-Yi Lin, Bang-Shuo Chen, Guan-Liang Chen, Jeng-Yue Wu, Hsin-Cheng Chiu, Shing-Yi Suen*, Preparation of porous PMMA/Na+–montmorillonite cation-exchange membranes for cationic dye adsorption, J. Membrane Sci., 2009, 326, 117-129. (SCI)

  60. Hsin-Cheng Chiu*, Yue-Wen Lin, Yi-Fong Huang, Chih-Kai Chuang, and Chorng-Shyan Chern, Polymer vesicles containing small vesicles within interior aqueous compartments and pH-responsive transmembrane channels, Angew. Chem. Int. Ed., 2008, 47, 1875-1878. (selected as a VIP and cover picture of the Journal) (SCI)

  61. Guo-Jing Chen, Ming-Cheng Yen, Jen-Ming Wang, Jiang-Jen Lin, and Hsin-Cheng Chiu*, Layered inorganic/enzyme nanohybrids with selectivity and structural stability upon interacting with biomolecules, Bioconjugate Chemistry, 2008, 19,138-144. (SCI)

  62. Chao-Shuan Chang, Ho-Sheng Ni, Shing-Yi Suen*, Wen-Chi Tseng, Hsin-Cheng Chiu, and C. Perry Chou, Preparation of inorganic-organic anion exchange membranes and their application in plasmid DNA and RNA separation, J. Membrane Sci., 2008, 311, 336-348.(SCI)

  63. Yuan-Hung Hsu, Wen-Hsuan Chiang, Mu-Chin Chen, Chorng-Shyan Chern, and Hsin-Cheng Chiu*, Effects of SDS on the thermo- and pH-sensitive structural changes of the PAAc-based copolymer containing both PNIPAAm and PEG grafts in water, Langmuir, 2006, 22, 6764-6770. (SCI)

  64. Chorng-Shyan Chern*, Hsin-Cheng Chiu, and Yu-Shiue Yang, Interactions between nonionic Triton X surfactants and cholesterol-containing phosphatidylcholine liposomes, J. Colloid and Interface Science, 2006, 302, 335-340. (SCI)

  65. Chorng-Shyan Chern*, Wei-Yih Chen, Hsin-Cheng Chiu, Fu-Hsiung Chang, Ming-Hung Hsieh, and Jia-Ren Tu, Interactions between amphiphilic graft copolymer-intercalated liposomes, Colloids and Surfaces A, 2006, 277, 44-51. (SCI)

  66. Yuan-Hung Hsu, Wen-Hsuan Chiang, Chien-Hsian Chen, Chorng-Shyan Chern, and Hsin-Cheng Chiu*, Thermally responsive interactions between the PEG and PNIPAAm grafts attached to the PAAc backbone and the corresponding structural changes of polymeric micelles in water, Macromolecules, 2005, 38, 9757-9765. (SCI)

  67. Hsin-Cheng Chiu*, Tin Hsiue and Wei-Young Chen, FTIR-ATR measurements of the ionization extent of acrylic acid within copolymerized methacrylated dextran/acrylic acid networks and its relation with pH/salt concentration-induced equilibrium swelling, Polymer, 2004, 45, 1627-1636. (SCI) 

  68. Chorng-Shyan Chern*, Hsin-Cheng Chiu and Yi-Ching Chuang, Synthesis and characterization of amphiphilic copolymers with PEG and cholesterol side chains, Polymer International, 2004, 53, 420-429. (SCI) 

  69. Yi-Jun Chen, Liang-Wei Huang, Hsin-Cheng Chiu and Sung-Chyr Lin*, Temperature-responsive polymer-assisted protein refolding, Enzyme & Microbial Technology, 2003, 32, 120-130. (SCI) 

  70. Hsin-Cheng Chiu*, Yi-Fong Lin and Shen-Hsiue Hung, Equilibrium swelling of copolymerized acrylic acid-methacrylated dextran networks: Effects of pH and neutral salt, Macromolecules, 2002, 35, 5235-5242. (SCI) 

  71. Hsin-Cheng Chiu*, Yuan-Hung Hsu and Pei-Jung Lin, Synthesis of pH-sensitive inulin hydrogels and characterization of their swelling properties, Journal of Biomedical Materials Research, 2002, 61, 146-152. (SCI) 

  72. Hsin-Cheng Chiu*, Yi-Fong Lin and Yuan-Hung Hsu, Effects of acrylic acid on preparation and swelling properties of pH-sensitive hydrogels, Biomaterials, 2002, 23, 1103-1112. (SCI) 

  73. Hsin-Cheng Chiu*, An-Tie Wu and Yi-Fong Lin, Synthesis and characterization of acrylic acid-containing dextran hydrogels, Polymer, 2001, 42, 1471-1479. (SCI)

  74. Jan-An Guu, Tzuoh-Miin Juang, Ging-Ho Hsiue* and Hsin-Cheng Chiu, Synthesis of dextran-(5-FU)-galactosamine conjugate through a tripeptide spacer group and its in vitro properties, J. Chin. Inst. Chem. Engrs., 2000, 31, 351-359. (SCI)

  75. Fu-Ya Wang and Hsin-Cheng Chiu*, Preparation of ethylcellulose-menadiol microcapsules and investigation of their properties in the presence of a protective colloid, Journal of Engineering, National Chung Hsing University, 2000, 11 (2), 23-34.

  76. Hsin-Cheng Chiu* and Chau-Hui Wang, Synthesis of temperature/pH-sensitive hydrogels containing disulfide linkages as crosslinks and their characterization, Polymer Journal, 2000, 32, 574-582. (SCI) 

  77. Shing-Yi Suen*, Shu-Ying Lin and Hsin-Cheng Chiu, The Effect of spacer arms on cibacron blue 3GA immobilization and lysozyme adsorption using regenerated cellulose membrane discs, Industrial & Engineering Chemistry Research, 2000, 39, 478-487. (SCI)

  78. Shing-Yi Suen*, Hsin-Cheng Chiu and Yi-Da Tsai, Polysaccharide-modified polysulfone hollow fibers as solid supports for affinity adsorption, Separation Science and Technology, 2000, 35, 1343-1362. (SCI)

  79. Sung-Chyr Lin*, Kai-Li Lin, Hsin-Cheng Chiu and Suryani Lin, Enhanced protein renaturation by temperature-responsive polymers, Biotech. Bioengr., 2000, 67, 505-512. (SCI)

  80. Hsin-Cheng Chiu*, Chun-Liang Lo and Fu-Ya Wang, Effects of protective colloids upon properties of ethylcellulose microcapsules prepared from various non-solvent addition methods, J. Chin. Inst. Chem. Engrs., 1999, 30, 491-499. (SCI)

  81. Hsin-Cheng Chiu, Chun-Hsia Hu and Chorng-Shyan Chern*, Preparation and characterization of amphiphilic poly (ethylene glycol) graft copolymers, Polymer Journal, 1999, 31, 535-541. (SCI) 

  82. Hsin-Cheng Chiu*, Ging-Ho Hsiue, Yang-Ping Lee and Liang-Wei Huang, Synthesis and characterization of pH-sensitive dextran hydrogels as a potential colon-specific drug delivery system, J. Biomaterials Sci. Polym. Ed., 1999, 10, 591-608. (SCI)

  83. Shing-Yi Suen*, Hsin-Cheng Chiu and Yi-Da Tsai, Surface modification of polysulfone microfiltration hollow fiber and its affinity adsorption, Journal of Engineering, National Chung Hsing University, 1998, 9 (2), 75-82. 

  84. Hsin-Cheng Chiu, Chorng-Shyan Chern*, Cheng-Kang Lee and Hui-Fang Chang, Synthesis and characterization of amphiphilic poly(ethylene glycol) graft copolymers and their potential applications as drug carriers, Polymer, 1998, 39, 1609-1616. (SCI)

  85. Hsin-Cheng Chiu, Pavla Kopeckova, Sharad S, Deshmane and Jindrich Kopecek*, Lysosomal degradability of poly(alpha-amino acids), Journal of Biomedical Materials Research, 1997, 34, 381-392. (SCI)

  86. Hsin-Cheng Chiu, Cestmir Konak, Pavla Kopeckova and Jindrich Kopecek, Enzymatic degradation of poly(ethylene glycol) modified dextrans, Journal of Bioactive and Compatible Polymers, 1994, 9, 338-410. (SCI)

  87. Hsin-Cheng Chiu, Samuel,Zalipsky, Pavla Kopeckova and Jindrich Kopecek**, enzymatic cactivity of chymotrypsin and its poly(ethylene glycol) conjugates toward low and high molecular weight substrates, Bioconjugate Chemistry, 1993, 4, 290-295. (SCI))

  88. Hsin-Cheng Chiu, Chun-Hsia Hu and Chorng-Shyan Chern*, Preparation and characterization of amphiphilic poly (ethylene glycol) graft copolymers, Polymer Journal, 1999, 31, 535-541. (SCI) 

  89. Hsin-Cheng Chiu*, Ging-Ho Hsiue, Yang-Ping Lee and Liang-Wei Huang, Synthesis and characterization of pH-sensitive dextran hydrogels as a potential colon-specific drug delivery system, J. Biomaterials Sci. Polym. Ed., 1999, 10, 591-608. (SCI)

  90. Shing-Yi Suen*, Hsin-Cheng Chiu and Yi-Da Tsai, Surface modification of polysulfone microfiltration hollow fiber and its affinity adsorption, Journal of Engineering, National Chung Hsing University, 1998, 9 (2), 75-82. 

  91. Hsin-Cheng Chiu, Chorng-Shyan Chern*, Cheng-Kang Lee and Hui-Fang Chang, Synthesis and characterization of amphiphilic poly(ethylene glycol) graft copolymers and their potential applications as drug carriers, Polymer, 1998, 39, 1609-1616. (SCI)

  92. Hsin-Cheng Chiu, Pavla Kopeckova, Sharad S, Deshmane and Jindrich Kopecek*, Lysosomal degradability of poly(alpha-amino acids), Journal of Biomedical Materials Research, 1997, 34, 381-392. (SCI)

  93. Hsin-Cheng Chiu, Cestmir Konak, Pavla Kopeckova and Jindrich Kopecek, Enzymatic degradation of poly(ethylene glycol) modified dextrans, Journal of Bioactive and Compatible Polymers, 1994, 9, 338-410. (SCI)

  94. Hsin-Cheng Chiu, Samuel,Zalipsky, Pavla Kopeckova and Jindrich Kopecek**, enzymatic cactivity of chymotrypsin and its poly(ethylene glycol) conjugates toward low and high molecular weight substrates, Bioconjugate Chemistry, 1993, 4, 290-295. (SCI))

logo.png

本網站著作權屬於國立清華大學 生醫工程與環境科學系 邱信程教授實驗室
電話:03-571-5131#34233

地址:(30013) 新竹市光復路二段101號 E-Mail:hscchiu@mx.nthu.edu.tw

Logo-3.jpg
bottom of page